Dr. Hansuo
Winner of the 5th Youth PI Research Assistance Scholarship from Origin
Excellent Innovation Center for Molecular Cell Biology, Chinese Academy of Sciences
参考知识 AI润色 35/1000 Reference knowledge AI polishing 35/1000 translation machine translation · General field Discovering and modifying biochemical reactions in nature that can accurately catalyze and label biomolecules in close proximity to space 划译 机翻 · 通用领域 Discovering and modifying biochemical reactions in nature that can accurately catalyze and label biomolecules in close proximity to space
Introduction
Dr. Shuo Han received his B.S. degree in chemistry, with a minor in computer science, from Tsinghua University in 2014. He earned his Ph.D. in chemical biology from Stanford University in 2020. From 2020 to 2022, he conducted postdoctoral research at the Stanford Institute for Stem Cell Biology and Regenerative Medicine. In December 2022, he joined the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (Shanghai Institute of Biochemistry and Cell Biology), where he established his laboratory.
His laboratory is dedicated to discovering and engineering catalytic reactions found in nature that can label biomolecules within proximity. By building these molecular labeling reactions in mammalian cells, the group aims to not only develop research tools for probing the spatial localization and interactions of molecules and cells, but also use these reactions as potential strategies for functional editing and manipulation of biological interactions.
Selected Publications
1.Shuojun Li†, Yinghui Men†, Zihan Wang†, Yingcheng Wu†, Hao Sun, Mingyang Yin, Xinrui Fan, Guiyun Deng, Zhicheng Yang, Tiange Yang, Yudian Xiao, Hu Zhou, Guangchuan Wang, Jia Fan, Chenqi Xu, Qiang Gao*, and Shuo Han*. Amplifying antigen-induced cellular responses with proximity labelling. Nature 2025, 647, 506–516. 2.Jiefu Li†, Shuo Han†, Hongjie Li, Namrata D. Udeshi, Tanya Svinkina, D. R. Mani, Chuanyun Xu, Ricardo Guajardo, Qijing Xie, Tongchao Li, David J. Luginbuhl, Bing Wu, Colleen N. McLaughlin, Anthony Xie, Pornchai Kaewsapsak, Stephen R. Quake, Steven A. Carr, Alice Y. Ting*, and Liqun Luo*. Cell-surface proteomic profiling in the fly brain uncovers wiring regulators. Cell 2020, 180, 373-386. 3.Furqan Fazal†, Shuo Han†, Kevin R. Parker, Pornchai Kaewsapsak, Jin Xu, Alistair N. Boettiger, Howard Y. Chang*, and Alice Y. Ting*. Atlas of subcellular RNA localization revealed by APEX-seq. Cell 2019, 178, 473-490.
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